DR6 polyclonal, anti-human antibody
€310.00
In stock
SKU
AC-ABV11514-100
Catalog Number: AC-ABV11514-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptor including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor 6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kB and JNK. DR6 is widely expressed in human tissues and cell lines.
Other Names:
Tumor necrosis factor receptor superfamily member 21, Death receptor 6, CD358, TNFRSF21, DR6
Primary Accession: O75509
Gene Name: TNFRSF21
Gene ID: 27242
Concentration (mg/ml): 0.5 mg/ml
Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptor including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor 6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kB and JNK. DR6 is widely expressed in human tissues and cell lines.
Other Names:
Tumor necrosis factor receptor superfamily member 21, Death receptor 6, CD358, TNFRSF21, DR6
Primary Accession: O75509
Gene Name: TNFRSF21
Gene ID: 27242
Concentration (mg/ml): 0.5 mg/ml
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