DR6 polyclonal, anti-human, mouse, rat antibody
€275.00
In stock
SKU
AC-ABV10172-100
Catalog Number: AC-ABV10172-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family thro µgh their death domain containing receptors, TNF-R1 and Fas. Several novel death receptor including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor 6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kB and JNK. DR6 is widely expressed in human tissues and cell lines.
Other Names:
Death Receptor 6, DR-6, DR 6
Primary Accession: Q9EPU5
Other Accession: EDL23398.1
Gene Name: Tnfrsf21
Gene ID: 94185
Concentration (mg/ml): 0.5 mg/ml
Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family thro µgh their death domain containing receptors, TNF-R1 and Fas. Several novel death receptor including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor 6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kB and JNK. DR6 is widely expressed in human tissues and cell lines.
Other Names:
Death Receptor 6, DR-6, DR 6
Primary Accession: Q9EPU5
Other Accession: EDL23398.1
Gene Name: Tnfrsf21
Gene ID: 94185
Concentration (mg/ml): 0.5 mg/ml
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