DRAGON (RGMB) Antibody (C-term) Blocking Peptide

DRAGON (RGMB) Antibody (C-term) Blocking Peptide

€363.00
In stock
SKU
AC-BP1421b
Catalog Number: AC-BP1421b
Size: 500 µg
Datasheet
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Background:
Repulsive Guidance Molecule B (RGMB) is primarily expressed in the central nervous system. RGM A and B both appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGMA appears in the neuroepithelium, and only RGMB in the peripheral nervous system. During development, both RGMA and B appear also in lung and in limb cartilage, while RGMB has additional expression domains in pancreas.

Other Names:
RGM domain family member B, DRG11-responsive axonal guidance and outgrowth of neurite, DRAGON, RGMB

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1421b was selected from the RGMB region of human DRAGON (RGMB). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: RGMB {ECO:0000303|PubMed:19324014, ECO:0000312|HGNC:HGNC:26896}

Gene ID: 285704
Primary Accession: Q6NW40
Other Accession: Q7TQ33
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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