DRAP1 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP18211a
Background:
Transcriptional repression is a general mechanism forregulating transcriptional initiation in organisms ranging fromyeast to humans. Accurate initiation of transcription fromeukaryotic protein-encoding genes requires the assembly of a largemultiprotein complex consisting of RNA polymerase II and generaltranscription factors such as TFIIA, TFIIB, and TFIID. DR1 is arepressor that interacts with the TATA-binding protein (TBP) ofTFIID and prevents the formation of an active transcription complexby precluding the entry of TFIIA and/or TFIIB into thepreinitiation complex. The protein encoded by this gene is acorepressor of transcription that interacts with DR1 to enhanceDR1-mediated repression. The interaction between this corepressorand DR1 is required for corepressor function and appears tostabilize the TBP-DR1-DNA complex.
Other Names:
Dr1-associated corepressor, Dr1-associated protein 1, Negative cofactor 2-alpha, NC2-alpha, DRAP1
Gene Name: DRAP1
Gene ID: 10589
Primary Accession: Q14919
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Transcriptional repression is a general mechanism forregulating transcriptional initiation in organisms ranging fromyeast to humans. Accurate initiation of transcription fromeukaryotic protein-encoding genes requires the assembly of a largemultiprotein complex consisting of RNA polymerase II and generaltranscription factors such as TFIIA, TFIIB, and TFIID. DR1 is arepressor that interacts with the TATA-binding protein (TBP) ofTFIID and prevents the formation of an active transcription complexby precluding the entry of TFIIA and/or TFIIB into thepreinitiation complex. The protein encoded by this gene is acorepressor of transcription that interacts with DR1 to enhanceDR1-mediated repression. The interaction between this corepressorand DR1 is required for corepressor function and appears tostabilize the TBP-DR1-DNA complex.
Other Names:
Dr1-associated corepressor, Dr1-associated protein 1, Negative cofactor 2-alpha, NC2-alpha, DRAP1
Gene Name: DRAP1
Gene ID: 10589
Primary Accession: Q14919
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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