DRD1 polyclonal, anti-human, mouse, rat antibody
€270.00
In stock
SKU
AC-ABO10608
Description: Rabbit IgG polyclonal antibody for Corticosteroid 11-beta-dehydrogenase isozyme 1 (HSD11B1) detection. Tested with WB, IHC-P in human, mouse, rat.
Protein Name: Corticosteroid 11-beta-dehydrogenase isozyme 1
Background:
Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7- ketocholesterol to 7-beta-hydroxycholesterol (By similarity). .
Other Names:
Corticosteroid 11-beta-dehydrogenase isozyme 1, 1.1.1.146, 11-beta-hydroxysteroid dehydrogenase 1, 11-DH, 11-beta-HSD1, Short chain dehydrogenase/reductase family 26C member 1, HSD11B1, HSD11, HSD11L, SDR26C1
Subcellular Localization: Endoplasmic reticulum membrane ; Single-pass type II membrane protein .
Tissue Specificity: Widely expressed. Highest expression in liver.
Gene ID: 3290
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human HSD11B1(16-33aa MAYYYYSANEEFRPEMLQ), different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids.
Calculated MW: 32401
Purification: Immunogen affinity purified.
Format: Lyophilized
Contents: Each vial contains 5mg BSA, 0.9 mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05 mg NaN3.
Concentration (mg/ml): Add 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Protein Name: Corticosteroid 11-beta-dehydrogenase isozyme 1
Background:
Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7- ketocholesterol to 7-beta-hydroxycholesterol (By similarity). .
Other Names:
Corticosteroid 11-beta-dehydrogenase isozyme 1, 1.1.1.146, 11-beta-hydroxysteroid dehydrogenase 1, 11-DH, 11-beta-HSD1, Short chain dehydrogenase/reductase family 26C member 1, HSD11B1, HSD11, HSD11L, SDR26C1
Subcellular Localization: Endoplasmic reticulum membrane ; Single-pass type II membrane protein .
Tissue Specificity: Widely expressed. Highest expression in liver.
Gene ID: 3290
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human HSD11B1(16-33aa MAYYYYSANEEFRPEMLQ), different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids.
Calculated MW: 32401
Purification: Immunogen affinity purified.
Format: Lyophilized
Contents: Each vial contains 5mg BSA, 0.9 mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05 mg NaN3.
Concentration (mg/ml): Add 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
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