DRD1 polyclonal, anti-human, mouse, rat

Background:
The members of the G protein coupled receptor family are distinguished by their slow transmitting response to ligand binding. These transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. β-adrenergic receptor binds to adrenaline activates adenylyl cyclase, while α2-adrenergic receptor binds to adrenaline inhibits adenylyl cyclase. The dopamine receptors are divided into two classes, D1 and D2, which differ in their functional characteristics in that D1 receptors stimulate adenylyl cyclase while D2 receptors inhibit adenylyl cyclase activity. Five different subtypes of dopamine receptor have been described to date. D1DR and D5DR belong to the D1 subclass, while D2DR, D3DR and D4DR belong to the D2 subclass.

Alternative Name:
DRD1, D(1A) dopamine receptor, D1A dopamine receptor, DADR, Dopamine D1 receptor, dopamine receptor D1, DR D1, DR D1A, DRD 1, DRD 1A, DRD1, DRD1, DRD1A,

Application Dilution:
WB:1:500-1:1,000
ICC:1:100-1:500
IHC:1:50-1:200

Specificity: DRD1 polyclonal antibody detects endogenous levels of DRD1 protein.

Immunogen:
recombinant protein

MW: 75 kDa

Swiss-Prot: P21728(Human) Q61616(Mouse) P18901(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.