DRD3 Polyclonal Antibody

Background:
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).

Research Area: Cancer, Neuroscience

Synonyms:
DRD3, D3DR, ETM1, FET1

Immunogen: Recombinant fusion protein of human DRD3 (NP_000787.2).

Swissprot: P35462
Gene ID: 1814

Calculated MW: 40 kDa/44 kDa
Observed MW: 44 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.