DRD4 Polyclonal Antibody

Background:
This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.

Research Area: Neuroscience

Synonyms:
D(2C) dopamine receptor, D(4) dopamine receptor (D(2C) dopamine receptor)., D(4) dopamine receptor, D4 dopamine receptor, D4DR, Dopamine D4 receptor, DRD 4, Drd4, DRD4

Immunogen: Synthetic peptide of human DRD4

Swissprot: P21917
Gene Accession: NP_000788

Calculated MW: 48 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:30-1:150

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-31480/sc-31481/sc-1439/sc-136169/sc-25649