Drosophila Parkin polyclonal (N-term), anti-drosophila
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SKU
AC-AP6414a
Catalog Number: AC-AP6414a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB8213
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB8213
Applications: WB
Datasheet
Request Information
Background:
Parkin is thought to play a role in the ubiquitin/proteasome pathway for protein degradation. The amino terminus bears sequence homology to ubiquitin while functionally it acts as a RING-type ubiquitin protein ligase (E3) that coordinates the transfer of ubiquitin to substrate proteins, thus targeting them for degradation by the proteasome. Mutations in the human version of the protein are known to cause autosomal recessive juvenile parkinsonism.
Other Names:
CG10523-PB; isoform B; Cg10523-pc; isoform c; PARKIN; park; parkin;
Target/Specificity:
This Drosophila Parkin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-111 amino acids from the N-terminal region of human Drosophila Parkin.
Antigen Region:
82-111
Antigen Type: Synthetic Peptide
Gene Name: PRKN
Gene ID: 40336
Primary Accession: Q7KTX7
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Parkin is thought to play a role in the ubiquitin/proteasome pathway for protein degradation. The amino terminus bears sequence homology to ubiquitin while functionally it acts as a RING-type ubiquitin protein ligase (E3) that coordinates the transfer of ubiquitin to substrate proteins, thus targeting them for degradation by the proteasome. Mutations in the human version of the protein are known to cause autosomal recessive juvenile parkinsonism.
Other Names:
CG10523-PB; isoform B; Cg10523-pc; isoform c; PARKIN; park; parkin;
Target/Specificity:
This Drosophila Parkin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-111 amino acids from the N-terminal region of human Drosophila Parkin.
Antigen Region:
82-111
Antigen Type: Synthetic Peptide
Gene Name: PRKN
Gene ID: 40336
Primary Accession: Q7KTX7
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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