DRP1 Polyclonal Antibody

Background:
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Cancer, Cell Biology, Metabolism, Neuroscience, Signal Transduction

Synonyms:
DLP1, dnm1l, DNM1L, Dnm1p/Vps1p-like protein, dnml1, DRP1, DVLP, Dymple, Dynamin 1 like, Dynamin family member proline-rich carboxyl-terminal domain less, Dynamin like protein, Dynamin related protein 1, Dynamin-1-like protein, Dynamin-like protein 4, Dynamin-like protein, Dynamin-like protein IV, Dynamin-related protein 1, DYNIV 11, EMPF, EMPF1, FLJ41912, HdynIV, VPS1

Immunogen: Recombinant Human Dynamin-1-like protein

Swissprot: O00429

Calculated MW: 81 kDa
Observed MW: 81 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Concentration: 2 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.