DRP1 Polyclonal Antibody

Background:
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Cancer, Cell Biology, Metabolism, Neuroscience, Signal Transduction

Synonyms:
DNM1L, DLP1, DRP1, DVLP, DYMPLE, EMPF, EMPF1, HDYNIV

Immunogen: Recombinant protein of human DRP1

Swissprot: O00429
Gene ID: 10059

Calculated MW: 60 kDa/78 kDa/79 kDa/80 kDa/81 kDa/82 kDa/83 kDa
Observed MW: 82 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.