DSC1 polyclonal, anti-human, mouse, rat

Background:
The desmosomal cadherin desmocollin DSC1 is expressed in upper epidermis where strong adhesion is required. DSC1 is a type I membrane protein (4) required for strong adhesion and barrier maintenance in epidermis and contributes to epidermal differentiation.The DSC1 gene comprises 17 exons spanning approximately 33 kb on 18q12.1.

Alternative Name:
Desmocollin-1, Desmocollin 1, Desmocollin1, Cadherin family member 1, DG2/DG3, DSC1, CDHF1

Application Dilution: WB: 1:500 - 1:2000

Specificity: DSC1 polyclonal antibody detects endogenous levels of DSC1 protein.

Immunogen:
Recombinant protein of human DSC1.

MW: ~ 100 kDa

Swis Prot.: Q08554

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.