DSC2 polyclonal, anti-human
€388.00
In stock
SKU
BS71520
Background:
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
Alternative Name:
DG2, DSC3, CDHF2, ARVD11, DGII/III,
Application Dilution: WB : 1:1000 - 1:2000
Specificity: DSC2 polyclonal antibody detects endogenous levels of DSC2 protein.
Immunogen:
Recombinant protein of human DSC2
MW: Predicted band size: 100 kDa, Observed band size: Refer to Figures
Swis Prot.: Q02487
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
Alternative Name:
DG2, DSC3, CDHF2, ARVD11, DGII/III,
Application Dilution: WB : 1:1000 - 1:2000
Specificity: DSC2 polyclonal antibody detects endogenous levels of DSC2 protein.
Immunogen:
Recombinant protein of human DSC2
MW: Predicted band size: 100 kDa, Observed band size: Refer to Figures
Swis Prot.: Q02487
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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