DSC2 polyclonal, anti-human, mouse , bovine

Background:
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.

Synonyms: ARVD11,CDHF2,DG2,DGII/III,DSC3,desmocollin-2

Cellular Location: Cytoplasm Cell membrane

Immunogen:
A synthetic peptide of human DSC2

Gene Symbol: DSC2

Gene ID: 1824

Swiss prot: Q02487

Calculated MW: 100/94kDa

Recommended dilution:
WB 1:8000-12000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.