DSC2 Polyclonal Antibody

Background:
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11.

Research Area: Cardiovascular, Signal Transduction

Synonyms:
ARVD11, Cadherin family member 2, CDHF2, Desmocollin 3, Desmocollin-2, Desmocollin-3, Desmocollin2, Desmosomal glycoprotein II and III, Desmosomal glycoprotein II, Desmosomal glycoprotein II/III, Desmosomal glycoprotein III, DG2, DGII/III, DKFZp686I11137, DSC 2, DSC2, DSC2, DSC3

Immunogen: Synthetic peptide of human DSC2

Swissprot: Q02487
Gene Accession: NP_077740

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-34307/sc-34311/sc-34312/sc-66862