DSCR1 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP6315c
Catalog Number: AC-AP6315c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB4671
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB4671
Applications: WB
Datasheet
Request Information
Background:
DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. The gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of DSCR1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
Other Names:
Calcipressin-1, Adapt78, Down syndrome critical region protein 1, Myocyte-enriched calcineurin-interacting protein 1, MCIP1, Regulator of calcineurin 1, RCAN1, ADAPT78, CSP1, DSC1, DSCR1
Target/Specificity:
This RCAN1/DSCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-252 amino acids from the C-terminal region of human DSCR1.
Antigen Region:
222-252
Antigen Type: Synthetic Peptide
Gene Name: RCAN1
Gene ID: 1827
Primary Accession: P53805
NCBI Accession: NP_004405.3;NP_981962.1;NP_981963.1
Other Accession: Q6IN33; Q9JHG6; O35847; Q3ZBP4; Q7Z555; Q6XXM7
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. The gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of DSCR1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
Other Names:
Calcipressin-1, Adapt78, Down syndrome critical region protein 1, Myocyte-enriched calcineurin-interacting protein 1, MCIP1, Regulator of calcineurin 1, RCAN1, ADAPT78, CSP1, DSC1, DSCR1
Target/Specificity:
This RCAN1/DSCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-252 amino acids from the C-terminal region of human DSCR1.
Antigen Region:
222-252
Antigen Type: Synthetic Peptide
Gene Name: RCAN1
Gene ID: 1827
Primary Accession: P53805
NCBI Accession: NP_004405.3;NP_981962.1;NP_981963.1
Other Accession: Q6IN33; Q9JHG6; O35847; Q3ZBP4; Q7Z555; Q6XXM7
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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