DSCR3 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6319a
Background:
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined.
Other Names:
Down syndrome critical region protein 3, Down syndrome critical region protein A, DSCR3, DCRA, DSCRA
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6319a was selected from the N-term region of human DSCR3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: VPS26C (HGNC:3044)
Gene ID: 10311
Primary Accession: O14972
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined.
Other Names:
Down syndrome critical region protein 3, Down syndrome critical region protein A, DSCR3, DCRA, DSCRA
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6319a was selected from the N-term region of human DSCR3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: VPS26C (HGNC:3044)
Gene ID: 10311
Primary Accession: O14972
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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