DSCR3 polyclonal (N-term), anti-human
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In stock
SKU
AC-AP6319a
Catalog Number: AC-AP6319a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2286
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2286
Applications: WB
Datasheet
Request Information
Background:
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined.
Other Names:
Down syndrome critical region protein 3, Down syndrome critical region protein A, DSCR3, DCRA, DSCRA
Target/Specificity:
This DSCR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DSCR3.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: VPS26C (HGNC:3044)
Gene ID: 10311
Primary Accession: O14972
NCBI Accession: NP_006043.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined.
Other Names:
Down syndrome critical region protein 3, Down syndrome critical region protein A, DSCR3, DCRA, DSCRA
Target/Specificity:
This DSCR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DSCR3.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: VPS26C (HGNC:3044)
Gene ID: 10311
Primary Accession: O14972
NCBI Accession: NP_006043.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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