DSCR3 Rabbit polyclonal antibody, anti-human, mouse

Background:
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region)| which spans 2.5 Mb on 21q22.2| has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome| including morphological features| hypotonia| and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined.

Research Area: Epigenetics and nuclear signaling

Synonyms: DSCR3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year