DSG1 polyclonal, anti-human

Background:
This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.

Synonyms: CDHF4, DG1, DSG, EPKHE, EPKHIA, PPKS1, SPPK1

Cellular Location: Cell junction Cell membrane Single-pass type I membrane protein desmosome

Immunogen:
Recombinant protein of human DSG1

Gene Symbol: DSG1

Gene ID: 1828

Swiss prot: Q02413

Calculated MW: 114kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.