DSG1 polyclonal, anti-human, mouse

Background:
Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.

Synonyms: DG1, DSG, CDHF4, PPKS1, SPPK1

Cellular Location: Cell junction Cell membrane Single-pass type I membrane protein desmosome

Immunogen:
A synthetic peptide of human DSG1

Gene Symbol: DSG1

Gene ID: 1828

Swiss prot: Q02413

Calculated MW: 114 kDa

Recommended dilution:
WB 1:200-1000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.