DSG2 Antibody (N-term T160) Blocking Peptide
€363.00
In stock
SKU
AC-BP7795a
Background:
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This protein is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in the DSG2 gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
Other Names:
Desmoglein-2, Cadherin family member 5, HDGC, DSG2, CDHF5
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7795a was selected from the N-term region of human DSG2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: DSG2
Gene ID: 1829
Primary Accession: Q14126
Other Accession: NP_001934
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This protein is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in the DSG2 gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
Other Names:
Desmoglein-2, Cadherin family member 5, HDGC, DSG2, CDHF5
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7795a was selected from the N-term region of human DSG2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: DSG2
Gene ID: 1829
Primary Accession: Q14126
Other Accession: NP_001934
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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