DSG2 polyclonal, anti-human

Background:
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.

Synonyms: HDGC, CDHF5, ARVC10, ARVD10, CMD1BB

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human DSG2

Gene Symbol: DSG2

Gene ID: 1829

Swiss prot: Q14126

Calculated MW: 122kDa

Recommended dilution:
IHC 1:100-300

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.