DSG2 Polyclonal Antibody

Background:
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.

Research Area: Cancer, Cardiovascular, Signal Transduction

Synonyms:
DSG2, CDHF5, HDGC

Immunogen: Recombinant fusion protein of human DSG2 (NP_001934.2).

Swissprot: Q14126
Gene ID: 1829

Calculated MW: 122 kDa
Observed MW: 150 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.