DSG2 polyclonal (N-term T160), anti-human
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In stock
SKU
AC-AP7795a
Catalog Number: AC-AP7795a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16855
Applications: FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16855
Applications: FC, WB
Datasheet
Request Information
Background:
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This protein is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in the DSG2 gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
Other Names:
Desmoglein-2, Cadherin family member 5, HDGC, DSG2, CDHF5
Target/Specificity:
This DSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-216 amino acids from the N-terminal region of human DSG2.
Antigen Region:
145-216
Antigen Type: Recombinant Protein
Gene Name: DSG2
Gene ID: 1829
Primary Accession: Q14126
NCBI Accession: NP_001934.2
Other Accession: NP_001934
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This protein is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in the DSG2 gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
Other Names:
Desmoglein-2, Cadherin family member 5, HDGC, DSG2, CDHF5
Target/Specificity:
This DSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-216 amino acids from the N-terminal region of human DSG2.
Antigen Region:
145-216
Antigen Type: Recombinant Protein
Gene Name: DSG2
Gene ID: 1829
Primary Accession: Q14126
NCBI Accession: NP_001934.2
Other Accession: NP_001934
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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