DSG3 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP14672a
Catalog Number: AC-AP14672a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34416
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34416
Applications: WB
Datasheet
Request Information
Background:
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
Other Names:
Desmoglein-3, 130 kDa pemphigus vulgaris antigen, PVA, Cadherin family member 6, DSG3, CDHF6
Target/Specificity:
This DSG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-36 amino acids from the N-terminal region of human DSG3.
Antigen Region:
8-36
Antigen Type: Synthetic Peptide
Gene Name: DSG3 (HGNC:3050)
Gene ID: 1830
Primary Accession: P32926
NCBI Accession: NP_001935.2
Other Accession: NP_001935.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
Other Names:
Desmoglein-3, 130 kDa pemphigus vulgaris antigen, PVA, Cadherin family member 6, DSG3, CDHF6
Target/Specificity:
This DSG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-36 amino acids from the N-terminal region of human DSG3.
Antigen Region:
8-36
Antigen Type: Synthetic Peptide
Gene Name: DSG3 (HGNC:3050)
Gene ID: 1830
Primary Accession: P32926
NCBI Accession: NP_001935.2
Other Accession: NP_001935.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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