DSPP polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family of proteins. The encoded preproprotein is secreted by odontoblasts and proteolytically processed to generate two principal proteins of the dentin extracellular matrix of the tooth, dentin sialoprotein and dentin phosphoprotein. These two protein products may play distinct but related roles in dentin mineralization. Mutations in this gene are associated with dentinogenesis imperfecta and dentin dysplasia. This gene is present in a gene cluster on chromosome 4. Allelic differences due to repeat polymorphisms have been found for this gene.

Synonyms: DFNA39, DGI1, DMP3, DPP, DSP

Cellular Location: Secreted extracellular matrix extracellular space

Immunogen:
Recombinant protein of human DSPP

Gene Symbol: DSPP

Gene ID: 1834

Swiss prot: Q9NZW4

Calculated MW: 131kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.