DST antibody (clone 1B10), anti-human
€435.00
In stock
SKU
AC-AT1822a
Catalog Number: AC-AT1822a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
Request Information AC-AT1822a">Request Information
Background:
This gene encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been reported that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration.
Other Names:
Dystonin, 230 kDa bullous pemphigoid antigen, 230/240 kDa bullous pemphigoid antigen, Bullous pemphigoid antigen 1, BPA, Bullous pemphigoid antigen, Dystonia musculorum protein, Hemidesmosomal plaque protein, DST, BP230, BP240, BPAG1, DMH, DT, KIAA0728
Antigen Type:
Recombinant Protein
Gene Name: DST (HGNC:1090)
Gene ID: 667
NCBI Accession: NP_001138241.1;NP_001138242.1;NP_001714.1;NP_056363.2;NP_899236.1
Primary Accession: Q03001
Other Accession: NM_183380
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been reported that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration.
Other Names:
Dystonin, 230 kDa bullous pemphigoid antigen, 230/240 kDa bullous pemphigoid antigen, Bullous pemphigoid antigen 1, BPA, Bullous pemphigoid antigen, Dystonia musculorum protein, Hemidesmosomal plaque protein, DST, BP230, BP240, BPAG1, DMH, DT, KIAA0728
Antigen Type:
Recombinant Protein
Gene Name: DST (HGNC:1090)
Gene ID: 667
NCBI Accession: NP_001138241.1;NP_001138242.1;NP_001714.1;NP_056363.2;NP_899236.1
Primary Accession: Q03001
Other Accession: NM_183380
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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