DTNBP1 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS6806
Background:
Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway.
Alternative Name:
DTBP1, DTNBP1, Dysbindin, Dysbindin-1, Dystrobrevin binding protein 1, Dystrobrevin-binding protein 1, Hermansky Pudlak syndrome 7 protein, Hermansky-Pudlak syndrome 7 protein, HPS7, HPS7 protein,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: DTNBP1 polyclonal antibody detects endogenous levels of DTNBP1 protein.
Immunogen:
Recombinant full length Human DTNBP1.
MW: ~ 39 kDa
Swis Prot.: Q96EV8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway.
Alternative Name:
DTBP1, DTNBP1, Dysbindin, Dysbindin-1, Dystrobrevin binding protein 1, Dystrobrevin-binding protein 1, Hermansky Pudlak syndrome 7 protein, Hermansky-Pudlak syndrome 7 protein, HPS7, HPS7 protein,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: DTNBP1 polyclonal antibody detects endogenous levels of DTNBP1 protein.
Immunogen:
Recombinant full length Human DTNBP1.
MW: ~ 39 kDa
Swis Prot.: Q96EV8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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