DTNBP1 polyclonal, anti-human, mouse

Background:
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Synonyms: BLOC1S8, DBND, HPS7, My031, SDY

Cellular Location: Cell junction Cytoplasm Cytoplasmic side Cytoplasmic vesicle Cytoplasmic vesicle membrane Endoplasmic reticulum Endosome membrane Melanosome membrane Nucleus Nucleus Peripheral membrane protein postsynaptic cell membrane postsynaptic density secretory vesicle synapse synaptic vesicle membrane

Immunogen:
Recombinant protein of human DTNBP1

Gene Symbol: DTNBP1

Gene ID: 84062

Swiss prot: Q96EV8

Calculated MW: 39kDa

Recommended dilution:
WB 1:500-2000, IF 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.