DTNBP1 Polyclonal Antibody

Background:
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Research Area: Cancer, Neuroscience

Synonyms:
DTNBP1, BLOC1S8, DBND, HPS7, My031, SDY, dysbindin

Immunogen: Recombinant fusion protein of human DTNBP1 (NP_115498.2).

Swissprot: Q96EV8
Gene ID: 84062

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.