DTX2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8881
Background:
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Alternative Name:
Probable E3 ubiquitin-protein ligase DTX2, Protein deltex-2, Deltex2, hDTX2, RING finger protein 58, DTX2, KIAA1528, RNF58
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: DTX2 polyclonal antibody detects endogenous levels of DTX2 protein.
Immunogen:
Recombinant full length Human DTX2.
MW: ~ 67kDa
Swis Prot.: Q86UW9
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Alternative Name:
Probable E3 ubiquitin-protein ligase DTX2, Protein deltex-2, Deltex2, hDTX2, RING finger protein 58, DTX2, KIAA1528, RNF58
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: DTX2 polyclonal antibody detects endogenous levels of DTX2 protein.
Immunogen:
Recombinant full length Human DTX2.
MW: ~ 67kDa
Swis Prot.: Q86UW9
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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