DTYMK polyclonal (C-term), anti-human, mouse
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In stock
SKU
AC-AP7060b
Catalog Number: AC-AP7060b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB5576
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB5576
Applications: WB
Datasheet
Request Information
Background:
Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.
Other Names:
Thymidylate kinase, dTMP kinase, DTYMK, CDC8, TMPK, TYMK
Target/Specificity:
This DTYMK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-194 amino acids from the C-terminal region of human DTYMK.
Antigen Region:
164-194
Antigen Type: Synthetic Peptide
Gene Name: DTYMK
Gene ID: 1841
Primary Accession: P23919
NCBI Accession: NP_036277.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.
Other Names:
Thymidylate kinase, dTMP kinase, DTYMK, CDC8, TMPK, TYMK
Target/Specificity:
This DTYMK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-194 amino acids from the C-terminal region of human DTYMK.
Antigen Region:
164-194
Antigen Type: Synthetic Peptide
Gene Name: DTYMK
Gene ID: 1841
Primary Accession: P23919
NCBI Accession: NP_036277.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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