DUS2L (K450) polyclonal, anti-human, mouse

Background:
Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR.

Alternative Name:
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like, Dihydrouridine synthase 2, Up-regulated in lung cancer protein 8, URLC8, tRNA-dihydrouridine synthase 2-like, hDUS2, DUS2L

Application Dilution:
WB: 1:500~1:1000

Specificity: URLC8 (K450) polyclonal antibody detects endogenous levels of URLC8 protein.

Immunogen:
Synthetic peptide, corresponding to amino acids 420-480 of Human URLC8.

MW: ~ 55 kDa

Swiss-Prot: Q9NX74

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.