DUSP12 polyclonal (Center), anti-human, mouse
€0.00
In stock
SKU
AC-AP16903c
Catalog Number: AC-AP16903c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35761
Applications: WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35761
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.
Other Names:
Dual specificity protein phosphatase 12, Dual specificity tyrosine phosphatase YVH1, DUSP12
Target/Specificity:
This DUSP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-191 amino acids from the Central region of human DUSP12.
Antigen Region:
162-191
Antigen Type: Synthetic Peptide
Gene Name: DUSP12
Gene ID: 11266
Primary Accession: Q9UNI6
NCBI Accession: NP_009171.1
Other Accession: NP_009171.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.
Other Names:
Dual specificity protein phosphatase 12, Dual specificity tyrosine phosphatase YVH1, DUSP12
Target/Specificity:
This DUSP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-191 amino acids from the Central region of human DUSP12.
Antigen Region:
162-191
Antigen Type: Synthetic Peptide
Gene Name: DUSP12
Gene ID: 11266
Primary Accession: Q9UNI6
NCBI Accession: NP_009171.1
Other Accession: NP_009171.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review