DUSP13 polyclonal (C-term), anti-human

DUSP13 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP18781b
Catalog Number: AC-AP18781b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB38755
Applications: WB
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Background:
Members of the protein-tyrosine phosphatase superfamilycooperate with protein kinases to regulate cell proliferation anddifferentiation. This superfamily is separated into two familiesbased on the substrate that is dephosphorylated. One family, thedual specificity phosphatases (DSPs) acts on both phosphotyrosineand phosphoserine/threonine residues. This gene encodes differentbut related DSP proteins through the use of non-overlapping openreading frames, alternate splicing, and presumed differenttranscription promoters. Expression of the distinct proteins fromthis gene has been found to be tissue specific and the proteins maybe involved in postnatal development of specific tissues. A proteinencoded by the upstream ORF was found in skeletal muscle, whereasthe encoded protein from the downstream ORF was found only intestis. In mouse, a similar pattern of expression was found.Multiple alternatively spliced transcript variants were described,but the full-length sequence of only some were determined.

Other Names:
Dual specificity protein phosphatase 13 isoform A, DUSP13A, Branching-enzyme interacting DSP, Muscle-restricted DSP, MDSP, DUSP13, BEDP, DUSP13A, MDSP

Target/Specificity:
This DUSP13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-173 amino acids from the C-terminal region of human DUSP13.

Antigen Region:
147-173

Antigen Type: Synthetic Peptide

Gene Name: DUSP13A
Gene ID: 128854680;51207
Primary Accession: Q6B8I1
NCBI Accession: NP_001007272.1;NP_001007273.1;NP_001007274.1
Other Accession: NP_001007272.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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