DUSP19 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP9029a
Background:
Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714).
Other Names:
Dual specificity protein phosphatase 19, Dual specificity phosphatase TS-DSP1, Low molecular weight dual specificity phosphatase 3, LMW-DSP3, Protein phosphatase SKRP1, Stress-activated protein kinase pathway-regulating phosphatase 1, SAPK pathway-regulating phosphatase 1, DUSP19, DUSP17, LMWDSP3, SKRP1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9029a was selected from the N-term region of human DUSP19. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: DUSP19 (HGNC:18894)
Gene ID: 142679
Primary Accession: Q8WTR2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714).
Other Names:
Dual specificity protein phosphatase 19, Dual specificity phosphatase TS-DSP1, Low molecular weight dual specificity phosphatase 3, LMW-DSP3, Protein phosphatase SKRP1, Stress-activated protein kinase pathway-regulating phosphatase 1, SAPK pathway-regulating phosphatase 1, DUSP19, DUSP17, LMWDSP3, SKRP1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9029a was selected from the N-term region of human DUSP19. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: DUSP19 (HGNC:18894)
Gene ID: 142679
Primary Accession: Q8WTR2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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