DUSP2 polyclonal (C-term), anti-human, mouse
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In stock
SKU
AC-AP9084B
Catalog Number: AC-AP9084B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB17124
Applications: FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB17124
Applications: FC, WB
Datasheet
Request Information
Background:
DUSP2 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.
Other Names:
Dual specificity protein phosphatase 2, Dual specificity protein phosphatase PAC-1, DUSP2, PAC1
Target/Specificity:
This DUSP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the C-terminal region of human DUSP2.
Antigen Region:
262-290
Antigen Type: Synthetic Peptide
Gene Name: DUSP2 (HGNC:3068)
Gene ID: 1844
Primary Accession: Q05923
NCBI Accession: NP_004409.1
Other Accession: Q05922
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
DUSP2 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.
Other Names:
Dual specificity protein phosphatase 2, Dual specificity protein phosphatase PAC-1, DUSP2, PAC1
Target/Specificity:
This DUSP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the C-terminal region of human DUSP2.
Antigen Region:
262-290
Antigen Type: Synthetic Peptide
Gene Name: DUSP2 (HGNC:3068)
Gene ID: 1844
Primary Accession: Q05923
NCBI Accession: NP_004409.1
Other Accession: Q05922
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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