DUSP5 antibody (clone 2F3), anti-human
€435.00
In stock
SKU
AC-AT1829a
Catalog Number: AC-AT1829a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF, E
Request Information AC-AT1829a">Request Information
Background:
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
Other Names:
Dual specificity protein phosphatase 5, Dual specificity protein phosphatase hVH3, DUSP5, VH3
Antigen Type:
Recombinant Protein
Gene Name: DUSP5
Gene ID: 1847
NCBI Accession: NP_004410.3
Primary Accession: Q16690
Other Accession: NM_004419
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
Other Names:
Dual specificity protein phosphatase 5, Dual specificity protein phosphatase hVH3, DUSP5, VH3
Antigen Type:
Recombinant Protein
Gene Name: DUSP5
Gene ID: 1847
NCBI Accession: NP_004410.3
Primary Accession: Q16690
Other Accession: NM_004419
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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