DVL1 Picoband polyclonal, anti-human, rat antibody

DVL1 Picoband polyclonal, anti-human, rat antibody

€310.00
In stock
SKU
AC-ABO10290
Catalog Number: AC-ABO10290
Size: 100 µg
Host: rabbit IgG
Applications: WB, IHC-P
Datasheet

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Description: Rabbit IgG polyclonal antibody for Band 3 anion transport protein (SLC4A1) detection. Tested with WB, IHC-P, IHC-F in human, mouse, rat.

Protein Name: Band 3 anion transport protein

Background:
Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine. .

Other Names:
Band 3 anion transport protein, Anion exchange protein 1, AE 1, Anion exchanger 1, Solute carrier family 4 member 1, CD233, SLC4A1, AE1, DI, EPB3

Subcellular Localization: Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Detected in the erythrocyte cell membrane and on the basolateral membrane of alpha-intercalated cells in the collecting duct in the kidney.

Tissue Specificity: Detected in erythrocytes (at protein level). Erythrocytes. .

Gene ID: 6521

Immunogen: E. coli-derived human Band 3 (Position: E28-N365). Human Band 3 shares 75.7% and 74.5% amino acid (aa) sequence identity with mouse and rat Band 3, respectively.

Calculated MW: 101792

Purification: Immunogen affinity purified.

Format: Lyophilized

Contents: Each vial contains 5mg BSA, 0.9 mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.

Concentration (mg/ml): Add 0.2 ml of distilled water will yield a concentration of 500 µg/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
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