DVL1 polyclonal (Center), anti-human, mouse
€0.00
In stock
SKU
AC-AP12326C
Catalog Number: AC-AP12326C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31716
Applications: WB, IF, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31716
Applications: WB, IF, IHC-P
Datasheet
Request Information
Background:
DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Other Names:
Segment polarity protein dishevelled homolog DVL-1, Dishevelled-1, DSH homolog 1, DVL1
Target/Specificity:
This DVL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-470 amino acids from the Central region of human DVL1.
Antigen Region:
442-470
Antigen Type: Synthetic Peptide
Gene Name: DVL1
Gene ID: 1855
Primary Accession: O14640
NCBI Accession: NP_004412.2
Other Accession: P54792; Q9WVB9; P51141; NP_004412.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Other Names:
Segment polarity protein dishevelled homolog DVL-1, Dishevelled-1, DSH homolog 1, DVL1
Target/Specificity:
This DVL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-470 amino acids from the Central region of human DVL1.
Antigen Region:
442-470
Antigen Type: Synthetic Peptide
Gene Name: DVL1
Gene ID: 1855
Primary Accession: O14640
NCBI Accession: NP_004412.2
Other Accession: P54792; Q9WVB9; P51141; NP_004412.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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