Dynamin (Ser774) polyclonal, anti-human, mouse, rat, bovine, dog, chicken, monkey
€536.00
In stock
SKU
252534
Catalog Nr.: 252534
Size: 0.1 ml
Isotype: Sheep Ig
Applications: E, WB, IF, IHC
Datasheet
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Size: 0.1 ml
Isotype: Sheep Ig
Applications: E, WB, IF, IHC
Datasheet
Request Information
Protein Family: Transporters
Pathway and Disease: Immune System, Infectious Diseases
Description:
Dynamin-1 is a microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Dynamin-1 is involved in vesicular trafficking processes, and is involved in receptor-mediated endocytosis. Phosphorylation of Ser774 by GSK3 has been shown to control activity-dependent bulk endocytosis of synaptic vesicles. This antibody is specific for the 95-kDa dynamin protein phosphorylated at Ser774. The antibody detects purified Dynamin phosphorylated in vitro by CdK5 but not by PKC. The antibody does not cross-react with other proteins subtrates of Cdk5 such as amphiphysin and synapsin.
Alternate Names: Dynamin-1, DNM1, DNM
Application Notes: E: 1:1,000; WB: 1:1,000; IHC: 1,1000; IF: 1:1,000
Accession No.: P21575
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser774 of rat dynamin.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Immune System, Infectious Diseases
Description:
Dynamin-1 is a microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Dynamin-1 is involved in vesicular trafficking processes, and is involved in receptor-mediated endocytosis. Phosphorylation of Ser774 by GSK3 has been shown to control activity-dependent bulk endocytosis of synaptic vesicles. This antibody is specific for the 95-kDa dynamin protein phosphorylated at Ser774. The antibody detects purified Dynamin phosphorylated in vitro by CdK5 but not by PKC. The antibody does not cross-react with other proteins subtrates of Cdk5 such as amphiphysin and synapsin.
Alternate Names: Dynamin-1, DNM1, DNM
Application Notes: E: 1:1,000; WB: 1:1,000; IHC: 1,1000; IF: 1:1,000
Accession No.: P21575
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser774 of rat dynamin.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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