DYNC1I1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70571
Background:
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Alternative Name:
DH IC-1, DYNC1I1, DNCI1, DNCIC1
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: DYNC1I1 polyclonal antibody detects endogenous levels of DYNC1I1 protein.
Immunogen:
Recombinant protein of human DYNC1I1.
MW: ~ 73 kDa
Swis Prot.: O14576
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Alternative Name:
DH IC-1, DYNC1I1, DNCI1, DNCIC1
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: DYNC1I1 polyclonal antibody detects endogenous levels of DYNC1I1 protein.
Immunogen:
Recombinant protein of human DYNC1I1.
MW: ~ 73 kDa
Swis Prot.: O14576
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review