Dyrk1B polyclonal antibody, anti-human, mouse

Background:
DYRK1B (dual specificity tyrosine phosphorylation regulated kinase 1B) encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of DYRK1B may be altered in tumor cells, and mutations in DYRK1B were found to cause abdominal obesity-metabolic syndrome 3. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Signal transduction

Synonyms: DYRK1B, MIRK, Dual specificity tyrosine-phosphorylation-regulated kinase 1B, Minibrain-related kinase, Mirk protein kinase

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year