Dysadherin polyclonal, anti-human antibody

Dysadherin polyclonal, anti-human antibody

€310.00
In stock
SKU
AC-ABO11074
Catalog Number: AC-ABO11074
Size: 100 µg
Host: rabbit IgG
Applications: WB, IHC-P
Datasheet

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Description: Rabbit IgG polyclonal antibody for Glutamate receptor 3 (GRIA3) detection. Tested with WB in human, mouse, rat.

Protein Name: Glutamate receptor 3

Background:
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. .

Other Names:
Glutamate receptor 3, GluR-3, AMPA-selective glutamate receptor 3, GluR-C, GluR-K3, Glutamate receptor ionotropic, AMPA 3, GluA3, GRIA3, GLUR3, GLURC

Subcellular Localization: Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Interaction with CNIH2 and CNIH3 promotes cell surface expression. .

Gene ID: 2892

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human GRIA3 (394-412aa RKAGYWNEYERFVPFSDQQ), identical to the related mouse and rat sequences.

Calculated MW: 101157

Purification: Immunogen affinity purified.

Format: Lyophilized

Contents: Each vial contains 5mg BSA, 0.9 mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05 mg NaN3.

Concentration (mg/ml): Add 0.2 ml of distilled water will yield a concentration of 500 µg/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
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