Dystrophin (clone DYS-48), anti-human, mouse, rat, chicken
€445.00
In stock
SKU
251744
Catalog Nr.: 251744
Size: 0.1 mg
Isotype: Mouse IgG2b
Applications: E, WB, IHC
Datasheet
Request Information
Size: 0.1 mg
Isotype: Mouse IgG2b
Applications: E, WB, IHC
Datasheet
Request Information
Protein Family: Cytoskeleton Proteins
Pathway and Disease: Neurodegenerative Disorders
Description:
Dystrophin anchors the extracellular matrix to the cytoskeleton via F-actin. Dystrophin is the ligand for dystroglycan. Dystrophin is a component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma.Defects in DMD are the cause of Duchenne muscular dystrophy (DMD). DMD is the most common form of muscular dystrophy; a sex-linked recessive disorder. It typically presents in boys aged 3 to 7 year as proximal muscle weakness causing waddling gait, toe-walking, lordosis, frequent falls, and difficulty in standing up and climbing up stairs.
Alternate Names: Dystrophin, DMD
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P11532
Antigen: Recombinant human dystrophin fragment.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Neurodegenerative Disorders
Description:
Dystrophin anchors the extracellular matrix to the cytoskeleton via F-actin. Dystrophin is the ligand for dystroglycan. Dystrophin is a component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma.Defects in DMD are the cause of Duchenne muscular dystrophy (DMD). DMD is the most common form of muscular dystrophy; a sex-linked recessive disorder. It typically presents in boys aged 3 to 7 year as proximal muscle weakness causing waddling gait, toe-walking, lordosis, frequent falls, and difficulty in standing up and climbing up stairs.
Alternate Names: Dystrophin, DMD
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P11532
Antigen: Recombinant human dystrophin fragment.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
| Is Featured? | No |
|---|
Write Your Own Review