Dystrophin polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Dystrophin, also known as DMD, is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane. It is mapped to Xp21.2-p21.1. This complex is variously known as the costamere or thedystrophin-associated protein complex. Many muscle proteins, such as α-dystrobrevin, syncoilin, synemin, sarcoglycan, dystroglycan, and sarcospan, colocalize with dystrophin at the costamere. Dystrophin is a protein located between the sarcolemma and the outermost layer of myofilaments in the muscle fiber (myofiber). It is a cohesive protein, linking actin filaments to another support protein that resides on the inside surface of each muscle fiber’s plasma membrane (sarcolemma).

Description:
Rabbit IgG polyclonal antibody for Dystrophin (DMD) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
Apo dystrophin antibody, BMD antibody, CMD3B antibody, DMD antibody, DMD_HUMAN antibody, Duchenne muscular dystrophy protein antibody, DXS142 antibody, DXS164 antibody, DXS206 antibody, DXS230 antibody, DXS239 antibody, DXS268 antibody, DXS269 antibody, DXS270 antibody, DXS272 antibody, Dystrophin antibody, Muscular dystrophy Duchenne and Becker types antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Dystrophin recombinant protein (Position: H3076-D3404). Human Dystrophin shares 100% amino acid (aa) sequence identity with mouse Dystrophin.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.