DZIP3 Polyclonal Antibody

Background:
function:E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.,pathway:Protein modification; protein ubiquitination.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with DAZ proteins.,tissue specificity:Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.,

Alternative Names:
DZIP3, KIAA0675, E3 ubiquitin-protein ligase DZIP3, DAZ-interacting protein 3, RNA-binding ubiquitin ligase of 138 kDa, hRUL138

Immunogen: The antiserum was produced against synthesized peptide derived from human DZIP3. AA range:681-730

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 140

GeneID: DZIP3

Storage: -20°C/1 year

NOTE: For Research Use Only