E Cadherin 1 CDH1 Picoband™ (clone 9G2), anti-human
€455.00
In stock
SKU
AC-ABO14856
Catalog Number: AC-ABO14856
Size: 100 µg
Isotype: Mouse
Applications: WB, IHC, IF, ICC, FC
Datasheet
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Size: 100 µg
Isotype: Mouse
Applications: WB, IHC, IF, ICC, FC
Datasheet
Request Information
Description: Anti-E Cadherin 1 CDH1 Antibody Picoband™ (monoclonal, 9G2) . Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.
Protein Function:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production. (Microbial infection) Serves as a receptor for Listeria monocytogenes; internalin A (InlA) binds to this protein and promotes uptake of the bacteria.
Other Names: Cadherin-1 {ECO:0000312|HGNC:HGNC:1748}, CAM 120/80, Epithelial cadherin, E-cadherin {ECO:0000312|HGNC:HGNC:1748}, Uvomorulin, CD324, E-Cad/CTF1, E-Cad/CTF2, E-Cad/CTF3, CDH1 (HGNC:1748)
Clone Name(s):
Clone: 9G2
Subcellular Localization: Trans-Golgi network. Cell membrane. Single-pass type I membrane protein. Endosome. Cell junction.
Gene ID: 999
Immunogen: E.coli-derived human E Cadherin recombinant protein (Position: A286-A703). Human E Cadherin shares 79.7% and 80.9% amino acid (aa) sequence identity with mouse and rat E Cadherin, respectively.
Calculated MW: 97456
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500 µg/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Concentration (mg/ml): Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Storage: Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Protein Function:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production. (Microbial infection) Serves as a receptor for Listeria monocytogenes; internalin A (InlA) binds to this protein and promotes uptake of the bacteria.
Other Names: Cadherin-1 {ECO:0000312|HGNC:HGNC:1748}, CAM 120/80, Epithelial cadherin, E-cadherin {ECO:0000312|HGNC:HGNC:1748}, Uvomorulin, CD324, E-Cad/CTF1, E-Cad/CTF2, E-Cad/CTF3, CDH1 (HGNC:1748)
Clone Name(s):
Clone: 9G2
Subcellular Localization: Trans-Golgi network. Cell membrane. Single-pass type I membrane protein. Endosome. Cell junction.
Gene ID: 999
Immunogen: E.coli-derived human E Cadherin recombinant protein (Position: A286-A703). Human E Cadherin shares 79.7% and 80.9% amino acid (aa) sequence identity with mouse and rat E Cadherin, respectively.
Calculated MW: 97456
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500 µg/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Concentration (mg/ml): Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Storage: Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
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