E-Selectin polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

Synonyms: ELAM-1, LECAM2, CD62E, ELAM1, SELE, ESEL

Cellular Location: Cytoplasm Cell membrane

Immunogen:
A synthetic peptide of human E-Selectin

Gene Symbol: E-Selectin

Gene ID: 6401

Swiss prot: P16581

Calculated MW: 63kDa

Recommended dilution:
WB 1:3000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.